Caffeine is the most commonly used psychoactive drug in the world, it is believed in the region of 90% of adult Americans consume caffeine every day. It is found in supplements, drugs, soda’s, some foods and of course Coffee. Caffeine works by binding to adenosine receptors, leaving them senseless. Adenosine builds up in our brains following neuro activity and is used as a signal to our brains that rest is needed. In essence Caffeine is blocking our brain from its tiredness receptors. Caffeine is abundant in a number of plant species, in particular Coffee, Yerba Mate, Guarana, and Tea Leaves.
L-Theanine is an amino acid and as per Caffeine can be found in Tea Leaves, quite the opposite to Caffeine, however, L-Theanine induces a relaxing sedative effect. It does this by inhibiting Glutamate receptors, Glutamate is a neurotransmitter that sends signals in the brain, L-Theanine binds to the brains glutamate receptors preventing overactivity in the brain and causing a calming relaxing effect without drowsiness.
Theanine and Caffeine both boast modest cognitive and focus enhancing properties in their own merit, however, both have negatives with caffeine triggering jitters and crashes and Theanine often having a sedative effect, but when combined, these two substances mechanisms significantly compliment each other. Theanine is a GABA agonist which counteracts the perceived negatives in caffeine leaving a lucid smooth focus and stimulation whilst Caffeine inhibits any feeling of drowsiness that may have been brought on by the Theanine.
Studies have evidenced a correct combination of L-Theanine & Caffeine to improve performance during cognitively demanding tasks - https://www.ncbi.nlm.nih.gov/pubmed/18681988
Whilst a noteable study conducted at the City University of New York showed a significant increase is behavioural performance, Electrophysiology (nervous system activity), cogntive function and attention. - http://jn.nutrition.org/content/138/8/1572S.long
L-Theanine and Caffeine have been studied and used for hundreds of years and are certainly the most researched Nootropic substances available. The simplicity, cost and effectiveness leaves this combination the perfect gateway nootropic to any new users.
Common practice is a ratio of 2:1 L-Theanine to Caffeine whilst a new users dosage will range from 100:50mg to 250:125mg.
Caffeine & L-Theanine are active ingredients in Vi-Brain Nootropic Supplement.